BDBM6568 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL386051::PD-173955::PD173955::US11136333, Compound PD173955

SMILES CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1

InChI Key InChIKey=VAARYSWULJUGST-UHFFFAOYSA-N

Data  3 KI  13 IC50  451 Kd  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6568   

TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd:  69nMAssay Description:Binding constant for ACVRL1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed